Course Slides, Case Studies and Summaries

Content, dates and details are subject to change and correction.

 

M

W

16th August

Session 0.1

Overview

18th

Session 1.1

Samples, Probability

23rd  

Session 1.2

Perfect Samples

25th 

Session 1.3

Discrete Models, Dice

30th                              

Session 1.4

Probability Computation

1st September                              

Session 1.5

Random Variables

6th                    

Holiday

Labor Day

8th                               

Session 1.6

Sample Size, Probability

13th                               

Session 1.7

Conditional Probability

15th 

Open Review Day

1st Hourly

20th                                

In-class Test Day

The First Hourly  

22nd    

Session 2.1

Clinical Trial Overview  

27th    

Session 2.2

Clinical Trial Sketch

29th

Session 2.3

Sample Survey and Design Fault Spot

4th October

Session 2.4

Design Fault Spot

6th

Session 2.5

Descriptive Statistics

11th  

No Classes

13th

Session 2.6

Summary Intervals

18th 

Open Review Day

2nd Hourly

20th   

In-class Test Day

The Second Hourly

25th                                 

Session 3.1

Overview, Confidence Intervals

27th                                  

Session 3.2

Confidence Intervals, Mean

1st November

Session 3.3

Confidence Intervals, Proportion

3rd November

Session 3.4

Overview, Hypothesis Testing

8th                                    

Session 3.5

Population Median Test

10th                                 

Session 3.6

Population Category Test

15th 

Open Review Day

3rd Hourly

17th   

In-class Test Day

The Third Hourly

22nd   

Open Review Day

Comprehensive Final Exam

25th                     

Holiday

Fall Break

29th    

Open Review Day

Comprehensive Final Exam

1st December  

Open Review Day

Comprehensive Final Exam

6th    

Final Exam

8th    

Final Exam

 

Course Begins

Sessions: Part One Fall

 

M

W

16th August

Session 0.1

Overview

18th

Session 1.1

Samples, Probability

23rd  

Session 1.2

Perfect Samples

25th 

Session 1.3

Discrete Models, Dice

30th                              

Session 1.4

Probability Computation

1st September                              

Session 1.5

Random Variables

6th                    

Holiday

Labor Day

8th                               

Session 1.6

Sample Size, Probability

13th                               

Session 1.7

Conditional Probability

15th 

Open Review Day

1st Hourly

20th                                

In-class Test Day

The First Hourly  

 

 

16th August / Session 0.1

Course Overview

 

18th August / Session 1.1

Samples, Probability

Probability

Case Study 1.1

Ellsberg's Urns I

Ellsberg's Urns II

 

Prediction and the Fair Die

Worksheet

Data

Comments

 

Counts, Proportions, Percentages Slides

 

The Color Bowl

Worksheet

Data

Comments

  

ÜSummaryÛ

 

23rd August / Session 1.2

Perfect Samples

 

Some Formulas

Perfect Sample Slides

 

Case Study 1.2.1

Case Study 1.2.2

 

Perfect Samples

Worksheet

Data

          Comments

 

Experiment

 

ÜSummaryÛ

 

25th August / Session 1.3

Discrete Models, Dice

Proportions

A Fair Three Sided Die

Random Variable

 

D6 to D3 Fair Dice, Simple Random Variable

          Worksheet

          Data

          Comments

 

A Pair of Dice

 

ÜSummaryÛ

 

 

30th August  / Session 1.4

 

Probability Computation

 

Events and Probability Rules

Rules Demo I - A Fair d6

Color Sequence Experiment

An Extended Example: The Binomial Distribution, Random Variables, Probability Rules and Expected Counts

Begin looking at the Color Sequence or Color Slot Machine Case Type – but avoid cases involving Conditional Probability yet.

ÜSummaryÛ

 

 

1st September / Session 1.5

 

Random Variables

 

Case Study 1.7

Case Study 1.8

Case Study 1.9

 

A Pair of Dice and a Random Variable

Worksheet

Data

Comments

 

ÜSummaryÛ

 

6th  September / Holiday

 

Labor Day

 

8th September / Session 1.6

 

Sample Size, Probability

 

Rare Event Approach

Sample Size and Probability

Case Study 1.10

Case Study 1.10A

 

Rare Event Comments

Rare Event Worksheet

Rare Event Data

 

 

ÜSummaryÛ

 

13th September / Session 1.7

Conditional Probability

 

Conditional Probability

Yet More Conditional Probability

How to compute a Conditional Probability

Conditional Probability Slides

 

A Demonstration - Three Dice

          Comments

          Worksheet

          Data

 

Case Study 1.11

Case Study 1.12

Case Study 1.13

An Application of Conditional Probability: Disease Screening

 

ÜSummaryÛ

 

15th September / Open Review Day / 1st Hourly

 

20th September / In-class Test Day / The First Hourly

Sessions: Part Two Fall

 

22nd    

Session 2.1

Clinical Trial Overview  

27th    

Session 2.2

Clinical Trial Sketch

29th

Session 2.3

Sample Survey

4th October

Session 2.4

Design Fault Spot

6th

Session 2.5

Descriptive Statistics

11th  

No Classes

13th

Session 2.6

Summary Intervals

18th 

Open Review Day

2nd Hourly

20th   

In-class Test Day

The Second Hourly

 

22nd September / Session 2.1

 

Clinical Trial Overview

 

History presents concise history of the Clinical Trial

Clinical Trial Design Overview

Steps / Clinical Trial

A Primer for Vaccines

A Primer for Cancer

Clinical Trial Subjects Bill of Rights

Supplemental Clinical Trial Notes

FDA Trials

 

VEGF and Wet Age-related Macular Degeneration

 

1st Hourly Scores by Monday

 

27th September / Session 2.2

 

Clinical Trial Sketch

 

Case Study - AIDSVAX

Case Study - Taxol and End Stage Cervical Cancer

Case Study - Gastric Adenocarcinoma

Case Study - Preeclampsia I

Case Study - Preeclampsia II

Case Study - Myocardial Infarction

Case Study - Traumatic Brain Injury

Case Study - Carbon Monoxide Intoxication

Case Study - Ocular Hypertension

Case Study - Diabetes Insipidus

Case Study - TheraVaxHIV      

Case Study - Pick's Disease

Case Study - Parkinson's Disease

Case Study - Herceptin

 

Informed Consent

Glossary defines terms associated with Clinical Trials

About Placebo


ÜSummaryÛ

 

29th September / Session 2.3

 

Sample Survey

 

Sample Survey Design Hypermedia Resources

 

http://www.hsph.harvard.edu/horp/classes/api214/Intro_Lecture.ppt

http://www.myhistory.org/historytopics/articles/public_opinion_polling.html

http://www.pbs.org/fmc/segments/progseg7.htm

http://www.hannibal.net/stories/101998/Pollstersrecall.html

http://www.hbstaff.com/political.htm

http://www.public.iastate.edu/~jhutter/406/lectureoutline.doc

http://www.cwrl.utexas.edu/~tonya/309m/class/paper4/bowser/opinpoll.htm

http://www.csudh.edu/dearhabermas/sampling01.htm

http://www.bartleby.com/65/po/poll.html

http://www.stat.ucla.edu/~rgould/m12s01/survey.pdf

http://wwwstat.ucla.edu/~rgould/m12s01/survey.pdf

http://www.kellogg.nwu.edu/faculty/weber/decs-439b/A_Primer_on_Polls.htm

http://fly.hiwaay.net/~jmcmulle/450polls.htm

http://stat.tamu.edu/~amang/307/J307ch01.pdf

 

Pew Center Links

http://people-press.org/

http://people-press.org/reports/

http://people-press.org/reports/display.php3?ReportID=12

http://people-press.org/reports/display.php3?ReportID=89

 

Sample Survey Design Outline

Survey Sampling

Respondent Rights

 

Supplemental Sample Survey Notes

Sampling Designs

glossary gives a glossary of terms used in Sample Survey Designs.

 

4th October / Session 2.4

 

Design Fault Spot

 

Design Faults – Clinical Trials

 

Clinical Trial Design Faults

Case Study 8

The ACCORD Study

What About Vioxx?

Gardasil: Prophylactic HPV Vaccine

Seven Steps to Understanding a Clinical Trial

Avastin and Choice of Endpoints: Overall Survival versus Progression-free Survival

 

 

Design Faults – Sample Surveys

 

Sample Survey Design Faults

Case Study 7 

The Pew Survey on Religion in the US - An example of a good survey

An IRS Survey on Taxpayer Attitudes on Taxes - An example of a dubious survey

 

ÜSummaryÛ

 

6th October / Session 2.5

 

Descriptive Statistics

The Calculator

Making Friends with Your Calculator

http://www.geocities.com/calculatorhelp/ti83

http://www.lrc.edu/mat/ti83_statistics.htm

http://www.math.tamu.edu/~khalman/calculator.htm

http://east.chclc.org/russo/ti3801.htm

http://www.willamette.edu/~mjaneba/help/TI-82-stats.htm

http://faculty.purduenc.edu/jkuhn/courses/previous/workbooks/301/lab1.pdf

http://instruct1.cit.cornell.edu/courses/arme210/TI83.pdf

 

Descriptive Statistics

 

Percentiles Sketch

 

Location - Measures of Location in Samples and Populations

Dispersion  

Case Study 3.1 – Serum Creatinine

Case Study 3.2 – Barrels of Monkeys

 

ÜSummaryÛ

 

11th October / No Classes

 

13th October / Session 2.6

 

Summary Intervals

 

Summary Intervals 1

Summary Intervals 2

 

Example – Summary Interval

 

Case Study 4 - Diseased Monkeys

Case Study 4.1 – Additional Case TBA

 

 

 

ÜSummaryÛ

 

 

18th October / Open Review Day / 2nd Hourly

Preparing for the Second Hourly

20th October / In-class Test Day / The Second Hourly

 

Sessions: Part Three Fall

25th                                 

Session 3.1

Overview, Confidence Intervals

27th                                  

Session 3.2

Confidence Intervals, Mean

1st November

Session 3.3

Confidence Intervals, Proportion

3rd November

Session 3.4

Overview, Hypothesis Testing

8th                                    

Session 3.5

Population Median Test

10th                                 

Session 3.6

Population Category Test

15th 

Open Review Day

3rd Hourly

17th   

In-class Test Day

The Third Hourly

 

25th October / Session 3.1

Overview, Confidence Intervals

27th October / Session 3.2

Confidence Estimation of the Population Mean

 

Families gives perspectives on Families of Samples and Families of Estimates

Family2 gives yet more fun insights on Families of Samples, Intervals, Errors

bell curves and sample means gives insights on the approximate behavior of sample means.

a few notes about statistical inference

Confidence Intervals

 

Verification of the 95% Confidence Principle

 

mean tables gives tables for means and proportions intervals and  proportions.

confidence interval steps

CI Mean Slides

Case Study 1

Case Study 2

 

ÜSummaryÛ

 

1st November / Session 3.3

Confidence Intervals, Proportion

CI Proportion Slides

proportions gives different viewpoints on the proportion in Statistics

Case Study 3

Case Study 4

 

ÜSummaryÛ

 

3rd November / Session 3.4

 

Overview, Hypothesis Testing

 

The Hypothesis Test and Decision Theory

The idea of a statistical test is explored here.

The idea of a statistical test is further clarified

Hypothesis Test Schematic

Hypothesis Test Slides    

 

 

8th November / Session 3.5

Population Median Test

Hypothesis Test – Population Median

Median Test Slides

Median Test Examples

median presents the idea of the Sign Test of the Median

median test presents the Sign Test of the Median

median table presents p-values for the median test

median pictures a graphical view of the sign test

median test steps

Case Study 7

Case Study 8

 

ÜSummaryÛ

 

10th November / Session 3.6

 

Hypothesis Test – Categorical Goodness-of-Fit

 

goodness of fit test slides

goodness of fit example

good tables give tables for the goodness-of-fit test

goodness of fit test steps

Case Study 9

Case Study 10

Verification of the 5% testing principle

Verification of the 5% testing principle - Fall 2007 Update

Verification of the 5% testing principle - Spring 2008 Update

 

ÜSummaryÛ

 

15th November / Open Review Day / 3rd Hourly

 

17th November / In-class Test Day / The Third Hourly

The Endgame

22nd   

Open Review Day

Comprehensive Final Exam

25th                     

Holiday

Fall Break

29th    

Open Review Day

Comprehensive Final Exam

1st December  

Open Review Day

Comprehensive Final Exam

6th    

Final Exam

8th    

Final Exam

Preparing for the Comprehensive Final

Comprehensive Final Archive

Course Ends